题 目：Smart Drug Delivery Triggered by Physiological Signals 报告人：Dr. Zhen Gu Assistant Professor, Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill | North Carolina State University, USA Email: zgu@email.unc.edu Abstract： Spurred by recent advanced in molecular pharmaceutics and materials chemistry, stimuli-responsive "smart" systems offer opportunities for delivering drugs in dose-, spatial- and temporal-controlled fashions. In this talk, I will discuss our ongoing efforts in using physiological signals, such as blood sugar level, enzyme activity and ATP gradient for on-demand drug release. I will first present the glucose-responsive closed-loop systems for biomimetic delivery of insulin. Next, I will discuss enzyme-activated formulations for delivery of cytokine, apoptotic executor and transcription factors in a programmed manner. Finally, I will introduce our recent work on ATP-mediated anticancer drug delivery. 地 点：化学楼图书馆二楼报告厅 时 间：2014年7月7日（星期一）上午10：00 联系人：沈群东 教授 欢迎各位老师和同学参加! 伟德源自英国始于1946高分子科学与工程系 高性能高分子材料与技术教育部重点实验室 |